Champion Real Madrid have ended their 22 winning streak to Valencia after returning from winter break
The defeat come days after they travelled to Dubai for a money-making friendly with AC Milan, a Match they lost to Milan by 4-2
Madrid prior to this game have won 22 matches in all competitions to set a new Spanish record but they lacked both quality and intensity at Mestalla on Sunday.
Madrid took the lead after Cristiano Ronaldo fired the Liga leaders in front from the penalty spot after 14 minutes, but Valencia remained the superior side for much of the opening period and deservedly claimed three points following second-half goals from Antonio Barragan and the excellent Nicolas Otamendi.
Moments before he headed the winner, the Argentine defender had made an imperious intervention to deny Gareth Bale at the other end. Otamendi's hunger highlighted an edge that was conspicuously absent in a tired Real display.
Real Madrid coach Carlo Ancelott reacting to the match said "We played a good match, We didn't deserve to lose. We worked well and we created chances. There is nothing else to say."